Longevity
The Alcohol J-Curve Did Not Survive Better Methods
Studies that separated lifelong abstainers from former drinkers found the protective dip largely disappeared.
Sep 27, 2026 • 10 min
Section
Longevity
Healthspan, cellular aging, and the interventions with real human data behind them.
Longevity
Muscle as an Endocrine Organ, Not Just an Engine
Contracting muscle releases signalling molecules that act elsewhere. The catalogue is growing faster than the clinical evidence.
Sep 23, 2026 • 10 min
Longevity
The Modifiable Share of Dementia Risk
Commission estimates put a substantial fraction of cases in reach of prevention. The estimate is a ceiling, not a promise.
Sep 19, 2026 • 11 min
Longevity
Sleep Regularity Is Predicting Outcomes Better Than Duration
Consistent timing has outperformed total hours in several recent cohort analyses. The mechanism is plausible but unproven.
Sep 15, 2026 • 9 min
Longevity
The Walking Dose-Response Curve Bends Early
Most of the mortality association in the step-count literature accumulates well before ten thousand.
Sep 14, 2026 • 8 min
Longevity
Resistance Training After Fifty: What the Trials Actually Show
Muscle remains trainable well into later decades. The variable that changes is recovery, not capacity.
Sep 12, 2026 • 10 min
Longevity
Creatine Beyond the Gym: The Cognitive Claims, Graded
The strength evidence is settled. The brain evidence is early, and the doses being discussed are not the ones on the label.
Sep 6, 2026 • 10 min
Longevity
Zone 2 Training: What the Evidence Actually Supports
Easy aerobic work is the backbone of every credible longevity protocol. The specific claims made for it are shakier than the practice.
Sep 1, 2026 • 11 min
Longevity
The Autophagy Paradox: Why Starving Your Cells Might Save Them
Recent meta-analyses suggest that the timing of nutrient deprivation is more critical than total caloric restriction for metabolic longevity.
Aug 18, 2026 • 12 min
Longevity
Muscle Mass: The Ultimate Longevity Insurance
New cohort data suggests lean mass and strength are among the strongest predictors of healthspan.
Aug 7, 2026 • 10 min
Longevity
The Longevity Supplement Audit: What Survives Human Trials
NAD precursors, resveratrol, metformin, rapamycin, taurine — graded on the strength of the human evidence rather than the mechanism story.
Jul 16, 2026 • 16 min
Longevity
VO2 Max Is the Strongest Modifiable Longevity Lever We Can Measure
Cardiorespiratory fitness separates mortality risk more sharply than smoking status. The training needed is more ordinary than the statistics suggest.
Jul 8, 2026 • 13 min