About the publication
Longevity and weight-loss reporting that shows its working.
Protocol .01 covers the science of healthspan and metabolic health for readers who want the study behind the headline. We publish slowly and cite carefully.
Primary sources first
Every claim traces to a published study, and we name the design: cohort, crossover, randomised trial, or animal model.
Effect sizes, stated plainly
We report absolute changes and sample sizes rather than relative percentages that flatter small findings.
No supplement affiliates
We do not take commissions on supplements, devices, or testing panels we write about.
Corrections in public
When we get something wrong, the correction stays on the article rather than being quietly edited out.
Medical disclaimer
Nothing on this site is medical advice or a substitute for a consultation with a qualified clinician. Longevity and weight-loss interventions — including fasting protocols, supplements, and prescription medication — carry individual risk. Speak to a clinician who knows your history before changing anything.